Growth assays have been automated for our genome-wide profiling prescreens, screens and follow-up confirmation assays. These robotic platforms comprise a central Packard Multiprobe II liquid handling instrument surrounded by 4 Tecan Genios Platereaders. The robotic system is coordinated by custom LabView software, which monitors growth, compound handling and sample storage. The software allows real-time growth analysis, and user-defined cell transfer and sample collection at specified generation times. All assay data from compound registration through analyzed data is stored in a central database. For more information, please contact or .